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CoEHAR paper reveals a new bias in medical evidence reviews: “positive results, negative advice”

CoEHAR paper reveals a new bias in medical evidence reviews: “positive results, negative advice”

Jan 29, 2026

Medical systematic reviews sit at the top of the evidence hierarchy. They are meant to guide clinicians, policymakers, and patients by carefully summarizing what research truly shows. But what happens when the results point in one direction — and the conclusions in...
A new systematic review by CoEHAR sheds light on the role of ENDS in managing post-cessation weight gain

A new systematic review by CoEHAR sheds light on the role of ENDS in managing post-cessation weight gain

Apr 7, 2025

Catania, April 7, 2025 – Weight gain remains one of the most feared side effects among those who decide to quit smoking. According to consumer opinions and preliminary industry data, reduced-risk products—such as electronic cigarettes—could represent a viable strategy...
New CoEHAR Umbrella review: no significant impact on lung function with E-cigarette use

New CoEHAR Umbrella review: no significant impact on lung function with E-cigarette use

Mar 17, 2025

The study systematically reviewed the respiratory effects of e-cigarette (EC) use, distinguishing between dual use, exclusive use, and naïve use. Twelve systematic reviews were analyzed No significant changes in respiratory function were observed across all patterns...
Umbrella Review: e-cigs are more effective for quitting than all other treatments

Umbrella Review: e-cigs are more effective for quitting than all other treatments

Dec 4, 2024

A groundbreaking umbrella review conducted by the Center of Excellence for the Acceleration of Harm Reduction (CoEHAR) at the University of Catania sheds new light on the efficacy of e-cigarettes as a smoking cessation aid. Published in Drug and Alcohol Dependence,...
New protocol aims to investigate the impact of different pattern of ENDS use on respiratory effects

New protocol aims to investigate the impact of different pattern of ENDS use on respiratory effects

Sep 6, 2024

CoEHAR researchers published a new protocol for an umbrella review to present all the evidence available on the respiratory effects of ENDS use by adults based on their pattern of use Electronic nicotine delivery systems have now become a well-established choice for...
CoEHAR: NO HEALTH RESPIRATORY EFFECTS REPORTED WITH ECIG SUBSTITUTION FOR SMOKING

CoEHAR: NO HEALTH RESPIRATORY EFFECTS REPORTED WITH ECIG SUBSTITUTION FOR SMOKING

Nov 7, 2023

A new review conducted on the available scientific literature showed no difference in respiratory parameters in human clinical tests on the respiratory effects of ENDS use in participants who smoke tobacco cigarettes Catania, 8 November, 2023 – The substitution of...
In Silico Science and Replica PI will attend the 6th THR summit, Athens 

In Silico Science and Replica PI will attend the 6th THR summit, Athens 

Nov 3, 2023

CoEHAR Director and the PI of the In Silico Science project will join experts, scientists and THR advocates at the 6th Summit on Tobacco Harm Reduction: Novel products, Research & Policy ( 25-26 September, Athens) by SCHORE The 6th Summit on Tobacco Harm...
6th Scientific Summit: latest findings by CoEHAR presented in Athens 

6th Scientific Summit: latest findings by CoEHAR presented in Athens 

Sep 26, 2023

Dr. Renée O’Leary, prof. Giovanni Li Volti and dr.Konstantinos Partsinevelos, CoEHAR researchers, attended  the 6th Summit on THR in Athens, presenting evidence on the use of ENDS as cessation aid and data from the latest studies on the effect of modified...
ENDS for smoking cessation: CoEHAR published the umbrella review protocol

ENDS for smoking cessation: CoEHAR published the umbrella review protocol

Sep 6, 2023

As part of the work of the In Silico Science project, dr. Renee O’Leary has recently published the protocol for an umbrella review to provide the widest overview of the clinical evidence on ENDS and cigarette smoking abstinence to an audience of researchers and...
CoEHAR researchers’ “guidebook”: how to identify data misinterpretations in ecig studies

CoEHAR researchers’ “guidebook”: how to identify data misinterpretations in ecig studies

May 3, 2023

Researchers from CoEHAR’s In Silico Science project have developed a two-step technique to identify spin bias, research reporting that results in an intentional or unintentional misinterpretation of research results Catania, 3 May 2023 – The results of scientific...
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Recent Posts

  • CoEHAR paper reveals a new bias in medical evidence reviews: “positive results, negative advice”
  • A new systematic review by CoEHAR sheds light on the role of ENDS in managing post-cessation weight gain
  • New CoEHAR Umbrella review: no significant impact on lung function with E-cigarette use
  • Umbrella Review: e-cigs are more effective for quitting than all other treatments
  • New protocol aims to investigate the impact of different pattern of ENDS use on respiratory effects

In Silico Science is a CoEHAR Project, all rights are reserved. In Silico Science is a Coehar investigator-initiated research. It is funded by ECLAT Srl (University of Catania spin-off) through a competitive grant from Global Action to End Smoking, a U.S. nonprofit 501(c)(3) private foundation. Global Action had no role in the planning or execution of this study, data analysis, or publication of results. Privacy Policy - Cookie Policy